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Hongfei Wu Selected Research

paeonol

2/2024MicroRNA let-7g links foam cell formation and adipogenic differentiation: A key regulator of Paeonol treating atherosclerosis-osteoporosis.
1/2024Paeonol Attenuates Atherosclerosis by Inhibiting Vascular Smooth Muscle Cells Senescence via SIRT1/P53/TRF2 Signaling Pathway.
10/2023Paeonol reduces microbial metabolite α-hydroxyisobutyric acid to alleviate the ROS/TXNIP/NLRP3 pathway-mediated endothelial inflammation in atherosclerosis mice.
1/2023Paeonol Attenuates the Endothelial-to-Mesenchymal Transition Induced by TGF-β1 in Human Umbilical Vein Endothelial Cells through ALK5- Smad2/3 Signaling Pathway.
1/2022Inhibiting vascular smooth muscle cell proliferation mediated by osteopontin via regulating gut microbial lipopolysaccharide: A novel mechanism for paeonol in atherosclerosis treatment.
1/2021Paeonol Attenuated Vascular Fibrosis Through Regulating Treg/Th17 Balance in a Gut Microbiota-Dependent Manner.
10/2020Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223.
1/2018Paeonol Attenuated Inflammatory Response of Endothelial Cells via Stimulating Monocytes-Derived Exosomal MicroRNA-223.
1/2018Paeonol Inhibits Oxidized Low-Density Lipoprotein-Induced Vascular Endothelial Cells Autophagy by Upregulating the Expression of miRNA-30a.
1/2017The Anti-atherosclerotic Effect of Paeonol against Vascular Smooth Muscle Cell Proliferation by Up-regulation of Autophagy via the AMPK/mTOR Signaling Pathway.
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Hongfei Wu Research Topics

Disease

15Atherosclerosis
04/2024 - 01/2017
7Hepatolenticular Degeneration (Wilson's Disease)
05/2023 - 02/2019
6Inflammation (Inflammations)
01/2024 - 01/2018
6Prostatic Neoplasms (Prostate Cancer)
01/2013 - 08/2004
5Neoplasms (Cancer)
04/2023 - 01/2012
3Osteosarcoma (Osteogenic Sarcoma)
04/2023 - 10/2019
3Hypersplenism (Anemia, Splenic)
10/2021 - 10/2016
3Infections
08/2020 - 08/2019
2Iron Overload
05/2023 - 01/2022
2Dysbiosis
08/2022 - 01/2022
2Necrosis
12/2021 - 08/2020
1Lipid Metabolism Disorders (Metabolism Disorders, Lipid)
04/2024
1Osteoporosis
02/2024
1Chronic Disease (Chronic Diseases)
01/2024
1Vascular Calcification
11/2023
1Sarcoma (Soft Tissue Sarcoma)
11/2023
1Osteoarthritis
10/2023
1Hypoxia (Hypoxemia)
04/2023
1Hemochromatosis (Bronze Diabetes)
01/2022
1Pure Red-Cell Aplasia
01/2022
1Dyslipidemias (Dyslipidemia)
01/2022
1Large Granular Lymphocytic Leukemia
01/2022
1Alcoholic Fatty Liver
12/2021
1Portal Hypertension
10/2021
1Aortic Dissection
09/2021
1Acute Lung Injury
09/2021
1Aplastic Anemia (Anemia, Hypoplastic)
03/2021
1Fibrosis (Cirrhosis)
01/2021
1Osteomyelitis
08/2020
1Diabetic Foot
08/2020
1Foot Ulcer
08/2020
1Ulcer
08/2020
1Urinary Bladder Neoplasms (Bladder Cancer)
12/2019
1Hypokalemia
12/2019
1Acidosis
12/2019
1Chronic Hepatitis B
11/2019
1Congenital Abnormalities (Deformity)
08/2019
1Secondary Hyperparathyroidism
01/2019
1Hoarseness
01/2019
1Obstructive Jaundice (Cholestatic Jaundice)
06/2018

Drug/Important Bio-Agent (IBA)

11paeonolIBA
02/2024 - 01/2015
7Apolipoproteins E (ApoE)IBA
03/2024 - 01/2017
5gualou xiebai baijiutangIBA
04/2024 - 01/2022
5CopperIBA
05/2023 - 02/2019
4LipidsIBA
02/2024 - 01/2022
3Proteins (Proteins, Gene)FDA Link
04/2023 - 04/2011
2MicroRNAs (MicroRNA)IBA
02/2024 - 01/2019
2Sirtuin 1IBA
01/2024 - 11/2023
2AcidsIBA
10/2023 - 01/2022
2CurcuminIBA
05/2023 - 12/2021
2Circular RNAIBA
04/2023 - 10/2019
2CateninsIBA
04/2020 - 10/2019
2Docetaxel (Taxotere)FDA Link
01/2013 - 04/2011
2Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
05/2008 - 10/2004
1CholesterolIBA
04/2024
1oxidized low density lipoproteinIBA
02/2024
1RNA (Ribonucleic Acid)IBA
11/2023
1N,N-dimethylarginine (asymmetric dimethylarginine)IBA
10/2023
1Drinking WaterIBA
10/2023
1EnzymesIBA
10/2023
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
04/2023
1Heavy MetalsIBA
08/2022
1Arachidonic Acid (Vitamin F)IBA
01/2022
120-hydroxy-5,8,11,14-eicosatetraenoic acidIBA
01/2022
1lipopolysaccharide AIBA
01/2022
114,15-dihydroxyeicosatrienoic acidIBA
01/2022
1metal transporting protein 1 (ferroportin)IBA
01/2022
1ApolipoproteinsIBA
01/2022
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2022
1Ferritins (Ferritin)IBA
01/2022
1LipopolysaccharidesIBA
01/2022
1OsteopontinIBA
01/2022
1Eosine Yellowish-(YS) (Eosin)IBA
12/2021
1Hematoxylin (Haematoxylon)IBA
12/2021
1Oxygen (Dioxygen)IBA
09/2021
1Receptor for Advanced Glycation End ProductsIBA
09/2021
1Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
03/2021
1Cyclosporine (Ciclosporin)FDA LinkGeneric
03/2021
1Matrix Metalloproteinases (MMPs)IBA
01/2021
1CollagenIBA
01/2021
1InflammasomesIBA
10/2020
1ChromatinIBA
01/2020
1ElectrolytesIBA
12/2019
1baicalinIBA
11/2019
1Cephalosporins (Cephalosporin Antibiotics)IBA
08/2019
1Phosphorus (Red Phosphorus)IBA
01/2019
1Parathyroid Hormone (Parathormone)IBA
01/2019
1CalciumIBA
01/2019

Therapy/Procedure

3Splenectomy
10/2021 - 10/2016
2Therapeutics
04/2023 - 01/2022
2Chinese Traditional Medicine (Traditional Chinese Medicine)
02/2020 - 01/2020
1Fecal Microbiota Transplantation
01/2022
1Bone Lengthening
08/2020
1Surgical Amputation (Amputations)
08/2020
1Debridement
08/2020
1Cystectomy
12/2019
1Osteotomy
08/2019
1Renal Dialysis (Hemodialysis)
01/2019
1Parathyroidectomy
01/2019
1Ligation
06/2018